01
Fundamental Methods and Models
Fundamental methods for image-based biophysical modeling and image synthesisBiophysical and data-driven models of disease progression, organ development, motion and deformation, image formation and acquisitionVirtual cell imagingDetailed mechanistic models (top–down) incorporating priors on geometry and physics of image acquisitionComplex spatio-temporal computational models of anatomical variability, organ physiology, and morphological changes
02
Machine and Deep Learning Techniques
Machine and deep learning techniques in image simulation and synthesisDeep learning methods including fully-supervised, semi-supervised, self-supervised, unsupervised, transfer, and multi-task learningDeep learning model architectures including Generative Adversarial Network (GAN), Variational Auto-Encoder (VAE), Flows, TransformersHandling uncertainty and incomplete data via simulation and synthesis techniquesImage synthesis in high dimensional spaces (vectors, tensors, spatio-temporal features, etc.)
03
Applications
Segmentation/registration across or within modalities to aid the learning of model parametersImaging protocol harmonization approaches across imaging systems, sites and time pointsImage synthesis for normalization and spatio-temporal intensity correctionCross modality (PET/MR, PET/CT, CT/MR, etc.) image synthesisSimulation and synthesis from large-scale databasesApplications of image synthesis in super resolution imaging and multi/cross-scale regressionApplications of image synthesis and simulation in medical image registration and segmentationApplications of synthesis and simulation to image reconstruction from sparse data or sparse viewsApplications of image synthesis in denoising, fusion reconstruction and real-time simulation of biophysical properties
04
Evaluation and Benchmarking
Automated techniques for quality assessment of simulations and synthetic imagesEvaluation and benchmarking of state of-the-art approaches in simulation and synthesisNormative and annotated datasets for benchmarking and learning modelsNovel ideas on evaluation metrics and methods in image-based simulation and image synthesis